Found 9 of ec50 for Glutamate receptor ionotropic, NMDA 2C
having polymerids = 9018,50002692 and
complexids = 50003607
having polymerids = 9018,50002692 and
complexids = 50003607
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 400nMAssay Description:Compound was evaluated for in vitro inhibition of [3H]-GABA release at NMDA receptor.More data for this Ligand-Target Pair
Affinity DataEC50: 1.90E+3nMAssay Description:Positive allosteric modulator activity at GluN2C NMDA receptor (unknown origin) expressed in CHO cells co-expressing GluN1a in the presence of L-glut...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 2.70E+3nMAssay Description:Positive allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
Affinity DataEC50: 6.60E+3nMAssay Description:Positive allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+4nMAssay Description:Positive allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 1.81E+4nMAssay Description:Compound was evaluated for in vitro inhibition of [3H]-TCP at NMDA receptor.More data for this Ligand-Target Pair
Affinity DataEC50: 3.70E+4nMAssay Description:Positive allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
Affinity DataEC50: 8.30E+4nMAssay Description:Positive allosteric modulation of EGFP-fused human GluN2C receptor expressed in HEK293T cells assessed as increase in glycine-induced channel current...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 1.40E+5nMAssay Description:Compound was evaluated for in vitro inhibition of cortical slice at NMDA receptorMore data for this Ligand-Target Pair